Article
Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder.
Neuroscience letters - 13 Feb 2008
Squassina Alessio, Lanktree Matthew, De Luca Vincenzo, Jain Umesh, Krinsky Marilee, Kennedy James L, Muglia Pierandrea
Abstract excerpt
Several lines of evidence from neuroimaging, pharmacology and genetics support the involvement of the dopaminergic system in the etiology of Attention Deficit Hyperactivity Disorder (ADHD). Previous candidate gene studies have investigated the association between a dinucleotide (CA)(n) repeat polymorphism, located 18.5 kb from the start codon of the DRD5 gene, and ADHD. Association between the 148 bp allele and...
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