Article
Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion.
PLoS pathogens - 6 Jan 2011
Atkinson Steve, Goldstone Robert J, Joshua George W P, Chang Chien-Yi, Patrick Hannah L, Cámara Miguel, Wren Brendan W, Williams Paul
Abstract excerpt
Yersinia pseudotuberculosis forms biofilms on Caenorhabditis elegans which block nematode feeding. This genetically amenable host-pathogen model has important implications for biofilm development on living, motile surfaces. Here we show that Y. pseudotuberculosis biofilm development on C. elegans is governed by N-acylhomoserine lactone (AHL)-mediated quorum sensing (QS) since (i) AHLs are produced in nematode...
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