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Article

E-cadherin synergistically induces hepatospecific phenotype and maturation of embryonic stem cells in conjunction with hepatotrophic factors.

Biotechnology and bioengineering - 5 Nov 2005

Dasgupta Anouska, Hughey Rebecca, Lancin Perry, Larue Lionel, Moghe Prabhas V

Abstract excerpt

Since effective cell sourcing is a major challenge for the therapeutic management of liver disease and liver failure, embryonic stem (ES) cells are being widely investigated as a promising source of hepatic-like cells with their proliferative and pluripotent capacities. Cell-cell interactions are crucial in embryonic development modulating adhesive and signaling functions; specifically, the cell-cell adhesion...

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Identifiers

PMID: 16167333
DOI: 10.1002/bit.20676

Genes

HGF
OSM
AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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