Article
HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Oct 2005
Hughes Michael G, Chong Tae W, Smith Robert L, Evans Heather L, Iezzoni Julia C, Sawyer Robert G, Rudy Christine K, Pruett Timothy L
Abstract excerpt
The second envelope protein at hypervariable region 1 (HVR1) has been implicated in contributing to hepatitis C virus (HCV)-host cell interactions and CD81 (a multifunctional protein) has been demonstrated to act as a cell surface receptor for HCV and may interact directly with HVR1. The purpose of the current study was to determine if certain HVR1 quasispecies variants more effectively associate with and infect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
