Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amplification and over‐expression of the <i>EGFR</i> and <i>erb</i>B‐2 genes in human esophageal adenocarcinomas

8 May 1993

Abstract excerpt

Esophageal cancer is one of the 10 most prevalent human cancers worldwide. The incidence of esophageal adenocarcinoma is on the rise and patients with this disease typically have very poor prognosis. Informative biomarkers would benefit the clinical management of this disease. We examined 13 cases with esophageal adenocarcinomas and 5 cases with Barrett's esophagus for amplification of the EGFR and erbB-2 genes....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Esophageal Cancer Research and Treatment
Share to HER2/EGFR in Cancer Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8098013
DOI: 10.1002/ijc.2910540209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amplification and over‐expression of the <i>EGFR</i> and <i>erb</i>B‐2 genes in human esophageal adenocarcinomasPMID 8098013Read ↗

EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagusSemantic proximity Read ↗

Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancerSemantic proximity Read ↗

Coamplification and coexpression of GRB7 and ERBB2 is found in high grade intraepithelial neoplasia and in invasive Barrett's carcinomaSemantic proximity Read ↗

<i>HER2</i>Amplification in Gastroesophageal AdenocarcinomaSemantic proximity Read ↗

<i>TNK</i><i>2</i> gene amplification is a novel predictor of a poor prognosis in patients with gastric cancerSemantic proximity Read ↗

Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinomaSemantic proximity Read ↗

EGFR protein overexpression and gene amplification in squamous cell carcinomas of the esophagusSemantic proximity Read ↗

c-myc Amplification Is Frequent in Esophageal Adenocarcinoma and Correlated with the Upregulation of VEGF-A ExpressionSemantic proximity Read ↗

Gains and Amplifications of <i>c-myc, EGFR</i>, and <i>20.q13</i> Loci in the No Dysplasia–Dysplasia–Adenocarcinoma Sequence of Barrett's EsophagusSemantic proximity Read ↗

Alterations in epidermal growth factor receptors 1 and 2 in esophageal squamous cell carcinomas.Semantic proximity Read ↗

Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinomaSemantic proximity Read ↗

Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.