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Article

Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population.

Anticancer research - 1 Jan 2000

Kim Jin Kyeoung, Kim Sehyun, Han Jin Hee, Kim Hyo Jin, Chong So Young, Hong Seong Pyo, Hwang Seong Gyu, Ahn Jung Yong, Cha Kwang Yul, Oh Doyeun, Kim Nam Keun

Abstract excerpt

BACKGROUND: Methylentetrahydrofolate reductase plays a central role in converting folate to methyl donor for DNA methylation. Genetic variations in folate metabolism are believed to contribute to the risk of acute lymphoblastic leukemia, colon, esophageal and stomach cancer, as well as cardiovascular and cerebrovascular diseases. MTHFR C677T and A1298C polymorphisms are known to be risk factors for gastric cancer...

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Identifiers

PMID: 16158971

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of 5,10-methylenetetrahydrofolate reductase and risk of stomach cancer in a Korean population.PMID 16158971Read ↗

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