Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population.

doi:10.1186/1471-2407-10-236

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Article

Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population.

BMC cancer - 26 May 2010

Cui Lian-Hua, Shin Min-Ho, Kweon Sun-Seog, Kim Hee Nam, Song Hye-Rim, Piao Jin-Mei, Choi Jin-Su, Shim Hyun Jeong, Hwang Jun Eul, Kim Hyeong-Rok, Park Young-Kyu, Kim Soo-Hyun

Abstract excerpt

BACKGROUND: This study was designed to investigate an association between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and the risk of gastric and colorectal cancer in the Korean population. METHODS: We conducted a population-based large-scale case-control study involving 2,213 patients with newly diagnosed gastric cancer, 1,829 patients with newly diagnosed colorectal cancer, and 1,700...

Topics

Aged
Asian People
Case-Control Studies
Colorectal Neoplasms
Female
Gene Frequency
Genetic Predisposition to Disease
Homozygote
Humans
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Methylenetetrahydrofolate Reductase (NADPH2)

Middle Aged

Odds Ratio

Phenotype

Polymorphism, Genetic

Republic of Korea

Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 20504332
DOI: 10.1186/1471-2407-10-236
PMCID: PMC2893109

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20504332-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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