Article
Signaling pathways implicated in alpha-melanocyte stimulating hormone-induced lipolysis in 3T3-L1 adipocytes.
Journal of cellular biochemistry - 1 Nov 2005
Cho Kyung-Joo, Shim Jung-Hyun, Cho Min-Chul, Choe Yong-Kyung, Hong Jin-Tae, Moon Dong-Chul, Kim Jong-Wan, Yoon Do-Young
Abstract excerpt
Melanocortins, besides their central roles, have also recently been reported to regulate adipocyte metabolism. In this study, we attempted to characterize the mechanism underlying alpha-melanocyte-stimulating hormone (MSH)-induced lipolysis, and compared it with that of the adrenocorticotrophin hormone (ACTH) in 3T3-L1 adipocytes. Similar to ACTH, MSH treatment resulted in the release of glycerol into the cell...
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