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Article

Molecular genetics of acute lymphoblastic leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Sept 2005

Armstrong Scott A, Look A Thomas

Abstract excerpt

From its beginnings two decades ago with the analysis of chromosomal translocation breakpoints, research into the molecular pathogenesis of acute lymphoblastic leukemia (ALL) has now progressed to the large-scale resequencing of candidate oncogenes and tumor suppressor genes in the genomes of ALL cases blocked at various developmental stages within the B- and T-cell lineages. In this review, we summarize the...

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Identifiers

PMID: 16155013
DOI: 10.1200/JCO.2005.05.047

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