Article
Identification of elements essential for transcription in Brugia malayi promoters.
Journal of molecular biology - 14 Oct 2005
Higazi Tarig B, Deoliveira Ana, Katholi Charles R, Shu Limin, Barchue Joseph, Lisanby Mark, Unnasch Thomas R
Abstract excerpt
Little is known concerning promoter structure in the filarial parasites. Recently, transient transfection methods have been developed for the human filarial parasite Brugia malayi. These methods have been employed to localize the promoter for the 70kDa heat shock protein (BmHSP70) to a region extending 394nt upstream from the initiating codon of the BmHSP70 open reading frame. Replacement mutagenesis was used to...
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