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Article

Positive and negative effects of deletions and mutations within the 5' flanking sequences of Plasmodium falciparum DNA polymerase delta.

Molecular and biochemical parasitology - 1 Jun 2002

Porter Megan E

Abstract excerpt

The DNA polymerase delta gene from Plasmodium falciparum is associated with a 1.76 kb 5' untranslated region and a promoter containing long homopolymeric (dA:dT) tracts and intrinsic DNA curvature. Here, a comprehensive deletion and mutational analysis of the DNA Pol(delta) upstream sequences has been undertaken to define functionally important regions. Removal of promoter-proximal DNA was shown to upregulate...

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PMID: 12076766
DOI: 10.1016/s0166-6851(02)00064-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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