Article
[Podocytopathie and transdifferentiation of the podocytes in human glomerulonephritis. An immunomorphological study].
Bulletin de l'Academie nationale de medecine - 1 Mar 2005
Bariety Jean, Bruneval Patrick, Meyrier Alain, Jacquot Christian
Abstract excerpt
Transdifferentiation is characterized by a loss of normal epitopes by differentiated cells, accompanied by the acquisition of new epitopes and new functions. Podocytes are differentiated epithelial cells that cover and adhere to the outer surface of the glomerular basement membrane (GBM). The podocyte/GBM complex contributes to the selective filter function of the glomerular tuft. We have shown that, in various...
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