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Article

Complexity of the major surface protease (msp) gene organization in Leishmania (Viannia) braziliensis: evolutionary and functional implications.

Parasitology - 1 Aug 2005

Victoir K, Arevalo J, De Doncker S, Barker D C, Laurent T, Godfroid E, Bollen A, Le Ray D, Dujardin J C

Abstract excerpt

The major surface protease (msp or gp63) of Leishmania plays a major role in the host-parasite interaction. We analysed here the structure of the msp gene locus in Leishmania (Viannia) braziliensis and compared it to results obtained in other species. Physical mapping of cosmid contigs revealed a minimum of 37 genes per haploid genome and at least 8 different msp gene families. Within the same organism, these...

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PMID: 16145937
DOI: 10.1017/s0031182005007535

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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