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Whole-Genome Sequencing and Comparative Genomic Analysis of <em>Leishmania </em>(<em>Viannia</em>)<em> naiffi</em> and <em>L. </em>(<em>Viannia</em>)<em> shawi</em> Reveal Species-Specific Genes and Novel Potential Drug Targets

2025-12-22

Abstract excerpt

This study presents the complete sequencing and comparative genomic analysis of Leishmania (Viannia) naiffi and Leishmania (Viannia) shawi, species of epidemiological relevance in the Brazilian Amazon. Genome assemblies yielded sizes of 32.13 Mb and 32.51 Mb, with 8,170 and 7,767 annotated genes, respectively. Predicted gene functions were primarily related to catalytic, binding, and ATP-dependent activities. Pang...

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Literature Corpus work
e5c2d6da-9141-5985-98dc-0eaf01d7ebf4
DOI
10.20944/preprints202512.1820.v1
Open publication

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Whole-Genome Sequencing and Comparative Genomic Analysis of <em>Leishmania </em>(<em>Viannia</em>)<em> naiffi</em> and <em>L. </em>(<em>Viannia</em>)<em> shawi</em> Reveal Species-Specific Genes and Novel Potential Drug TargetsDOI 10.20944/preprints202512.1820.v1
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