Article
A mathematical model for a new mechanism of phenotypic variation in malaria.
Parasitology - 1 Aug 2005
Recker M, Al-Bader R, Gupta S
Abstract excerpt
The Py235 merozoite rhoptry protein of the rodent malaria agent Plasmodium (yoelii) yoeli is encoded by the Py235 multigene family whose members are transcribed during the parasite's asexual life-cycle in a fashion where single schizonts subsequently give rise to sets of merozoites containing distinct Py235 transcripts. Homologues of Py235 are found in other malaria species, and antibodies to both Py235 and P....
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