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Article

A rhoptry-protein-associated mechanism of clonal phenotypic variation in rodent malaria.

Nature - 15 Apr 1999

Preiser P R, Jarra W, Capiod T, Snounou G

Abstract excerpt

The recognition and invasion of host cells are mediated by components of the apical complex of the ookinete, sporozoite and merozoite stages of Plasmodium parasites. The paired rhoptries (organelles involved in host-cell recognition) in the apical complex contain many proteins of as-yet unknown function. In the rodent malaria agent P. yoelii yoelii, a multigene family codes for merozoite rhoptry proteins of...

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PMID: 10217144
DOI: 10.1038/19309

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