Article
Regulation of hippocampal gene expression is conserved in two species subjected to different stressors and antidepressant treatments.
Biological psychiatry - 1 Feb 2006
Alfonso Julieta, Frick Luciana R, Silberman Dafne M, Palumbo María L, Genaro Ana M, Frasch Alberto C
Abstract excerpt
BACKGROUND: Chronic stress has significant effects on hippocampal structure and function. We have previously identified nerve growth factor (NGF), membrane glycoprotein 6a (M6a), the guanine nucleotide binding protein (G protein) alpha q polypeptide (GNAQ), and CDC-like kinase 1 (CLK-1) as genes regulated by psychosocial stress and clomipramine treatment in the hippocampus of tree shrews. These genes encode...
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