Article
Selection of and recombination between minor variants lead to the adaptation of an avian coronavirus to primate cells.
Biochemical and biophysical research communications - 21 Oct 2005
Fang Shou Guo, Shen Shuo, Tay Felicia P L, Liu D X
Abstract excerpt
An interesting question posed by the current evidence that severe acute respiratory syndrome coronavirus may be originated from an animal coronavirus is how such an animal coronavirus breaks the host species barrier and becomes zoonotic. In this report, we study the chronological order of genotypic changes in the spike protein of avian coronavirus infectious bronchitis virus (IBV) during its adaptation to a...
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