Article
Chlamydia trachomatis variant with nonfusing inclusions: growth dynamic and host-cell transcriptional response.
The Journal of infectious diseases - 1 Oct 2005
Xia Minsheng, Suchland Robert J, Bumgarner Roger E, Peng Tao, Rockey Daniel D, Stamm Walter E
Abstract excerpt
We compared growth rate and host-cell transcriptional responses of a Chlamydia trachomatis variant strain and a prototype strain. Growth dynamics were estimated by 16S rRNA level and by inclusion-forming units (IFUs) at different times after infection in HeLa cells. When inoculated at the same multiplicity of infection and observed 24-48 h after infection, the variant 16S rRNA transcriptional level was 3%-4% that...
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