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Article

An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection.

FEMS microbiology letters - 1 Aug 2017

Xue Yaohua, Zheng Heping, Mai Zhida, Qin Xiaolin, Chen Wentao, Huang Tao, Chen Daxiang, Zheng Lei

Abstract excerpt

Single-dose azithromycin is recommended for treating Chlamydia trachomatis infections. Here, we established an in vitro cell model of azithromycin-induced persistent infection. Azithromycin inhibited the replication of C. trachomatis in a dose-time-dependent manner. Electron microscopy indicated that small inclusions in the induced model contained enlarged, aberrant and non-infectious reticulate bodies. RT-PCR...

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Identifiers

PMID: 28854672
DOI: 10.1093/femsle/fnx145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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