[Cloning of the genes associated with the pathogenesis of pregnancy induced hypertension using subtractive hybridization].

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Article

[Cloning of the genes associated with the pathogenesis of pregnancy induced hypertension using subtractive hybridization].

Zhonghua fu chan ke za zhi - 1 Oct 2001

Yao Y, Shi J, Yan W

Abstract excerpt

OBJECTIVE: To clone the genes related to pregnancy induced hypertension (PIH) for the study of PIH pathogenesis. METHODS: The differential expressed cDNA of PIH and normal pregnant placenta were cloned using modified polymerase chain reaction based subtractive hybridization. The differential cDNA were sequenced. RESULTS: Among 86 clones from subtractive hybridization, 14 clones containing differential expressed...

Topics

Cloning, Molecular
DNA, Complementary
Expressed Sequence Tags
Female
Genetic Predisposition to Disease
Humans
Hypertension, Pregnancy-Induced
Molecular Sequence Data
Nucleic Acid Hybridization
Pregnancy
Sequence Analysis, DNA

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Open in PubMed

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PMID: 16134518

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