Article
Functional dissection of the Suppressor of UnderReplication protein of Drosophila melanogaster: identification of domains influencing chromosome binding and DNA replication.
Genetica - 1 Jul 2005
Kolesnikova T D, Makunin I V, Volkova E I, Pirrotta V, Belyaeva E S, Zhimulev I F
Abstract excerpt
The Suppressor of UnderReplication (SuUR) gene controls the DNA underreplication in intercalary and pericentric heterochromatin of Drosophila melanogaster salivary gland polytene chromosomes. In the present work, we investigate the functional importance of different regions of the SUUR protein by expressing truncations of the protein in an UAS-GAL4 system. We find that SUUR has at least two separate...
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