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Article

A comparative study on endoscopic ulcer healing of omeprazole versus rabeprazole with respect to CYP2C19 genotypic differences.

Digestive diseases and sciences - 1 Sept 2005

Ando Takashi, Kato Haruki, Sugimoto Naohito, Nagao Yasuyuki, Seto Nobuyuki, Hongo Hitoshi, Kajikawa Hirokazu, Isozaki Yutaka, Shimozawa Makoto, Naito Yuji, Yoshida Norimasa, Ishizaki Takashi, Yoshikawa Toshikazu

Abstract excerpt

Omeprazole is mainly metabolized in the liver by CYP2C19, a genetically determined enzyme, while rabeprazole is mainly nonenzymatically degraded with a minor involvement by CYP2C19. We investigated the gastric ulcer healing effect of omeprazole versus rabeprazole evaluated endoscopically with reference to the different CYP2C19 genotypes. Eighty patients with active gastric ulcer were treated with a daily dose of...

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Identifiers

PMID: 16133961
DOI: 10.1007/s10620-005-2907-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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