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Article

A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26.

Annals of neurology - 1 Sept 2005

Puranam Ram S, Jain Satish, Kleindienst Amber M, Saxena Shilpa, Kim Myeong-Kyu, Kelly Changizi Barbara, Padma M V, Andrews Ian, Elston Robert C, Tiwari Hemant K, McNamara James O

Abstract excerpt

Inheritance patterns in twins and multiplex families led us to hypothesize that two loci were segregating in subjects with juvenile myoclonic epilepsy (JME), one predisposing to generalized tonic-clonic seizures (GTCS) and a second to myoclonic seizures. We tested this hypothesis by performing genome-wide scan of a large family (Family 01) and used the results to guide analyses of additional families. A locus was...

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PMID: 16130088
DOI: 10.1002/ana.20598

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NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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