Article
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation.
Developmental biology - 15 Oct 2005
Jülich Dörthe, Hwee Lim Chiaw, Round Jennifer, Nicolaije Claudia, Schroeder Joshua, Davies Alexander, Geisler Robert, Lewis Julian, Jiang Yun-Jin, Holley Scott A
Abstract excerpt
The Tübingen large-scale zebrafish genetic screen completed in 1996 identified a set of five genes required for orderly somite segmentation. Four of them have been molecularly identified and three were found to code for components of the Notch pathway, which are required for the coordinated oscillation of gene expression, known as the segmentation clock, in the presomitic mesoderm (PSM). Here, we show that the...
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