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Article

An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis.

Journal of virology - 1 Apr 2012

Prasad Alka, Lu Michael, Lukac David M, Zeichner Steven L

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is linked to several neoplastic diseases: Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). KSHV replicates actively, via a controlled gene expression program, but can also remain latent. It had been thought that the transition from latent to lytic replication was controlled exclusively by the replication and transcription...

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Identifiers

PMID: 22345480
DOI: 10.1128/JVI.06617-11
PMCID: PMC3318647

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Source receipt: pubmed, retrieved 7 Sept 2026.

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