Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A long-term genetic survey of an ungulate population reveals balancing selection acting on MHC through spatial and temporal fluctuations in selection.

Heredity - 1 Nov 2005

Charbonnel N, Pemberton J

Abstract excerpt

We explored a 13-year genetic survey of the major histocompatibility complex (MHC) and neutral loci of the Soay sheep population of St Kilda to test the existence and causes of balancing selection at the MHC. The sheep population experiences demographic fluctuations, partly driven by the nematode Teladorsagia circumcincta. The spatial differentiation detected at the MHC was comparable to that at neutral loci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Data Collection
Share to Genetic Drift
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Major Histocompatibility Complex

Share to Models, Genetic

Share to Selection, Genetic

Source

Identifiers

PMID: 16118661
DOI: 10.1038/sj.hdy.6800735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A long-term genetic survey of an ungulate population reveals balancing selection acting on MHC through spatial and temporal fluctuations in selection.PMID 16118661Read ↗

Temporal variation at the MHC class IIb in wild populations of the guppy (Poecilia reticulata).Semantic proximity Read ↗

Major histocompatibility complex variation associated with juvenile survival and parasite resistance in a large unmanaged ungulate population.Semantic proximity Read ↗

Selection and recombination drive the evolution of MHC class II DRB diversity in ungulates.Semantic proximity Read ↗

Spatial and temporal patterns of neutral and adaptive genetic variation in the endangered African wild dog (Lycaon pictus).Semantic proximity Read ↗

Spatial patterns of neutral and functional genetic variations reveal patterns of local adaptation in raccoon (Procyon lotor) populations exposed to raccoon rabies.Semantic proximity Read ↗

Density-related changes in selection pattern for major histocompatibility complex genes in fluctuating populations of voles.Semantic proximity Read ↗

Cis-regulatory evolution in a wild primate: Infection-associated genetic variation drives differential expression of MHC-DQA1 in vitro.Semantic proximity Read ↗

Both selection and drift drive the spatial pattern of adaptive genetic variation in a wild mammal.Semantic proximity Read ↗

Spatio-temporal variation in the strength and mode of selection acting on major histocompatibility complex diversity in water vole (Arvicola terrestris) metapopulations.Semantic proximity Read ↗

Lack of Spatial Immunogenetic Structure among Wolverine (Gulo gulo) Populations Suggestive of Broad Scale Balancing Selection.Semantic proximity Read ↗

Drift rather than selection dominates MHC class II allelic diversity patterns at the biogeographical range scale in natterjack toads Bufo calamita.Semantic proximity Read ↗

Enhanced selection for MHC diversity in social tuco-tucos.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.