Article
Glucocorticoid-remediable aldosteronism.
Cardiology in review - 1 Jan 2000
McMahon Graham T, Dluhy Robert G
Abstract excerpt
Glucocorticoid remediable aldosteronism (GRA) appears to be the most common monogenic form of human hypertension. As a result of chimeric gene duplication, aldosterone is ectopically synthesized in the zona fasciculata of the adrenal gland under the control of adrenocorticotropin (ACTH). Affected individuals are typically hypertensive, often with onset in youth, and demonstrate refractoriness to standard...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
