Hepatic necroinflammation and fibrosis in patients with genotypes Ba and C, core-promoter and precore mutations.

doi:10.1111/j.1365-2893.2005.00629.x

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Article

Hepatic necroinflammation and fibrosis in patients with genotypes Ba and C, core-promoter and precore mutations.

Journal of viral hepatitis - 1 Sept 2005

Yuen M-F, Tanaka Y, Ng I O-L, Mizokami M, Yuen J C-H, Wong D K-H, Yuan H-J, Sum S-M, Chan A O-O, Lai C-L

Abstract excerpt

SUMMARY: The role of infection with hepatitis B virus (HBV) genotypes on liver histology is largely unknown. The aim of study was to investigate the relationships between HBV genotypes (B, C), core-promoter (CP) and precore mutants and liver histology in 66 patients. Liver biopsies were scored by histologic activity index (HAI). HBV genotypes were determined by enzyme-linked immunosorbent assay (ELISA). Eighteen...

Topics

Genotype
Hepatitis B Core Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Cirrhosis
Mutation
Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 16108767
DOI: 10.1111/j.1365-2893.2005.00629.x

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