Article
Viral genotype and hepatitis B virus DNA levels are correlated with histological liver damage in HBeAg-negative chronic hepatitis B virus infection.
The American journal of gastroenterology - 1 Feb 2002
Chan Henry Lik-Yuen, Tsang Steven Woon-Choi, Liew Chook-Tiew, Tse Chi-Hang, Wong May-Ling, Ching Jessica Yuet-ling, Leung Nancy Wai-Yee, Tam John Siu-Lun, Sung Joseph Jao-Yiu
Abstract excerpt
OBJECTIVES: We aimed to study the relationship between the hepatitis B virus (HBV) genotypes, core promoter/precore stop codon mutations, and histological liver damage among hepatitis B e antigen (HBeAg)-negative patients. METHODS: Liver biopsy specimens of 55 HBeAg-negative chronic HBV-infected patients were studied. A histological activity index was scored for degree of necroinflammation (HAI-NI) and fibrosis...
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