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Article

Segregation of urine calcium excretion in families ascertained for nephrolithiasis: evidence for a major gene.

Kidney international - 1 Sept 2005

Loredo-Osti J C, Roslin Nicole M, Tessier Josée, Fujiwara T Mary, Morgan Kenneth, Bonnardeaux Alain

Abstract excerpt

BACKGROUND: The quantitative genetics of urine calcium excretion has not been established. It is a trait of interest because hypercalciuria is commonly found in subjects with nephrolithiasis. The aim of this study was to model the segregation of this trait in a sample of French-Canadian families ascertained through a stone former. METHODS: Major gene, polygenic, and mixed models were fit to 24-hour urine calcium...

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Identifiers

PMID: 16105027
DOI: 10.1111/j.1523-1755.2005.00490.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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