Article
A population-based approach to assess the heritability and distribution of renal handling of electrolytes.
Kidney international - 1 Dec 2017
Moulin Flore, Ponte Belen, Pruijm Menno, Ackermann Daniel, Bouatou Yassine, Guessous Idris, Ehret Georg, Bonny Olivier, Pechère-Bertschi Antoinette, Staessen Jan A, Paccaud Fred, Martin Pierre-Yves, Burnier Michel, Vogt Bruno, Devuyst Olivier, Bochud Murielle
Abstract excerpt
The handling of electrolytes by the kidney is essential for homeostasis. However, the heritability of these processes, the first step in gene discovery, is poorly known. To help clarify this, we estimated the heritability of serum concentration, urinary excretion, renal clearance, and fractional excretion of sodium, potassium, magnesium, calcium, phosphate, and chloride in a population-based study. Nuclear...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.