Article
Genetics of Paget's disease of bone.
Clinical science (London, England : 1979) - 1 Sept 2005
Daroszewska Anna, Ralston Stuart H
Abstract excerpt
PDB (Paget's disease of bone) is a common condition characterized by focal increases in bone turnover affecting one or more sites throughout the skeleton. Genetic factors are important in the pathogenesis of PDB and many families have been described where PDB is inherited in an autosomal-dominant fashion. Several candidate loci for susceptibility to PDB and related syndromes have been identified by genome-wide...
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