Article
The normalized inhibitory quotient of boosted protease inhibitors is predictive of viral load response in treatment-experienced HIV-1-infected individuals.
AIDS (London, England) - 2 Sept 2005
Winston Alan, Hales Gill, Amin Janaki, van Schaick Erno, Cooper David A, Emery Sean
Abstract excerpt
OBJECTIVE: The normalized inhibitory quotient (NIQ) has been proposed as a measure for refining the precision of HIV resistance testing when selecting antiretroviral therapy (ART). We undertook an assessment of NIQ and 48-week virological outcome in patients commencing ritonavir-boosted protease inhibitor (PI) regimens. DESIGN: A cohort of 87 HIV-infected individuals who all had extensive prior exposure to ART...
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