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Article

VirR, a response regulator critical for Listeria monocytogenes virulence.

Molecular microbiology - 1 Sept 2005

Mandin Pierre, Fsihi Hafida, Dussurget Olivier, Vergassola Massimo, Milohanic Eliane, Toledo-Arana Alejandro, Lasa Iñigo, Johansson Jörgen, Cossart Pascale

Abstract excerpt

Signature-tagged mutagenesis (STM) was used to identify new genes involved in the virulence of the Gram-positive intracellular pathogen Listeria monocytogenes. One of the mutants isolated by this technique had the transposon inserted in virR, a gene encoding a putative response regulator of a two-component system. Deletion of virR severely decreased virulence in mice as well as invasion in cell-culture...

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PMID: 16102006
DOI: 10.1111/j.1365-2958.2005.04776.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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