Article
Construction and characterization of Listeria monocytogenes mutants with in-frame deletions in the response regulator genes identified in the genome sequence.
Infection and immunity - 1 May 2005
Williams Tatjana, Bauer Susanne, Beier Dagmar, Kuhn Michael
Abstract excerpt
Two-component systems are widely distributed in prokaryotes where they control gene expression in response to diverse stimuli. To study the role of the sixteen putative two-component systems of Listeria monocytogenes systematically, in frame deletions were introduced into 15 out of the 16 response regulator genes and the resulting mutants were characterized. With one exception the deletion of the individual...
Topics
- Animals
- Bacterial Proteins
- COS Cells
- Caco-2 Cells
- Cell Line
- Female
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Genes, Regulator
- Genome, Bacterial
- Humans
- Listeria monocytogenes
- Listeriosis
- Mice