Article
Membrane interaction of neuropeptide Y detected by EPR and NMR spectroscopy.
Biochimica et biophysica acta - 15 Aug 2005
Thomas Lars, Scheidt Holger A, Bettio Andrea, Huster Daniel, Beck-Sickinger Annette G, Arnold Klaus, Zschörnig Olaf
Abstract excerpt
Neuropeptide Y (NPY) is one of the most abundant peptides in the central nervous system of mammals. It belongs to the best-conserved peptides in nature, i.e., the amino acid sequences of even evolutionary widely separated species are very similar to each other. Using porcine NPY, which differs from human NPY only at position 17 (a leucine residue exchanged for a methionine), labeled with a TOAC spin probe at the...
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