Article
The genetic contribution of the TNFa11 microsatellite allele and the TNFb + 252*2 allele in Japanese RA.
Clinical and experimental rheumatology - 1 Jan 2000
Takeuchi F, Nabeta H, Hong G H, Kawasugi K, Mori M, Matsuta K, Kuwata S, Murayama T, Nakano K
Abstract excerpt
OBJECTIVES: The contribution of the microsatellite polymorphisms of TNFa and TNFb, and the TNFB + 252 (TNFB) dimorphism to the pathogenesis of rheumatoid arthritis (RA) was studied among Japanese patients. METHODS: The TNFa and TNFb microsatellite polymorphisms, and the TNFB dimorphism were determined in Japanese RA patients and normal subjects using electrophoresis followed by specific PCR amplification....
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