Article
Molecular pathogenesis of movement disorders: are protein aggregates a common link in neuronal degeneration?
Current opinion in neurology - 1 Aug 1999
Schulz J B, Dichgans J
Abstract excerpt
Abnormal protein aggregation has been postulated to explain the molecular basis for many neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and prion diseases, as well as trinucleotide repeat disorders. The recent findings that mutations in alpha-synuclein lead to autosomal-dominant, early-onset Parkinson's disease in some families and that alpha-synuclein is found in Lewy bodies of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
