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Article

Transcriptional response of Candida albicans upon internalization by macrophages.

Eukaryotic cell - 1 Oct 2004

Lorenz Michael C, Bender Jennifer A, Fink Gerald R

Abstract excerpt

The opportunistic fungal pathogen Candida albicans is both a benign gut commensal and a frequently fatal systemic pathogen. The interaction of C. albicans with the host's innate immune system is the primary factor in this balance; defects in innate immunity predispose the patient to disseminated candidiasis. Because of the central importance of phagocytic cells in defense against fungal infections, we have...

Topics

Animals
Candida albicans
Cell Line
Fungal Proteins
Gene Expression Profiling
Genes, Fungal
Gluconeogenesis
Glycolysis
Glyoxylates
Macrophages
Mice
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Virulence

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Identifiers

PMID: 15470236
DOI: 10.1128/EC.3.5.1076-1087.2004
PMCID: PMC522606

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