Article
Natural antisense LHCGR could make sense of hypogonadism, male-limited precocious puberty and pre-eclampsia.
Molecular and cellular endocrinology - 28 Sept 2005
Chambers Anne E, Banerjee Subhasis
Abstract excerpt
The pleiotropic effects of human chorionic gonadotrophin (hCG), the key regulator of human pregnancy, are dependent upon cell surface expression of its functional cognate receptor LHCGR in the placental trophoblasts, corpus luteum, uterus, vascular endothelial and smooth muscle cells. Additionally, lutenizing hormone-mediated signalling failure has often been linked to activating/inactivating mutations in LHCGR....
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