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Article

The temporal requirements for insulin signaling during development in Drosophila.

PLoS biology - 1 Sept 2005

Shingleton Alexander W, Das Jayatri, Vinicius Lucio, Stern David L

Abstract excerpt

Recent studies have indicated that the insulin-signaling pathway controls body and organ size in Drosophila, and most metazoans, by signaling nutritional conditions to the growing organs. The temporal requirements for insulin signaling during development are, however, unknown. Using a temperature-sensitive insulin receptor (Inr) mutation in Drosophila, we show that the developmental requirements for Inr activity...

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Identifiers

PMID: 16086608
DOI: 10.1371/journal.pbio.0030289
PMCID: PMC1184592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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