Article
Copy Number Variation in TAS2R Bitter Taste Receptor Genes: Structure, Origin, and Population Genetics.
Chemical senses - 1 Oct 2016
Roudnitzky Natacha, Risso Davide, Drayna Dennis, Behrens Maik, Meyerhof Wolfgang, Wooding Stephen P
Abstract excerpt
Bitter taste receptor genes (TAS2Rs) harbor extensive diversity, which is broadly distributed across human populations and strongly associated with taste response phenotypes. The majority of TAS2R variation is composed of single-nucleotide polymorphisms. However, 2 closely positioned loci at 12p1...
Topics
- Alleles
- Amino Acid Sequence
- DNA Copy Number Variations
- Genetics, Population
- Humans
- Receptors, G-Protein-Coupled
- Sequence Alignment
- Taste
- Taste Perception
- Taste Receptors, Type 2