Article
Phenotypical heterogeneity linked to adipose tissue dysfunction in patients with Type 2 diabetes.
Clinical science (London, England : 1979) - 1 Oct 2016
Barchetta Ilaria, Angelico Francesco, Del Ben Maria, Di Martino Michele, Cimini Flavia Agata, Bertoccini Laura, Polimeni Licia, Catalano Carlo, Fraioli Antonio, Del Vescovo Riccardo, Morini Sergio, Baroni Marco Giorgio, Cavallo Maria Gisella
Abstract excerpt
Adipose tissue (AT) inflammation leads to increased free fatty acid (FFA) efflux and ectopic fat deposition, but whether AT dysfunction drives selective fat accumulation in specific sites remains unknown. The aim of the present study was to investigate the correlation between AT dysfunction, hepatic/pancreatic fat fraction (HFF, PFF) and the associated metabolic phenotype in patients with Type 2 diabetes (T2D)....
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