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Article

Amphipathic alpha-helix mediates the heterodimerization of soluble guanylyl cyclase.

Zoological science - 1 Jul 2005

Shiga Takumi, Suzuki Norio

Abstract excerpt

Soluble guanylyl cyclase (soluble GC) is an enzyme consisting of alpha and beta subunits and catalyzes the conversion of GTP to cGMP. The formation of the heterodimer is essential for the activity of soluble GC. Each subunit of soluble GC has been shown to comprize three functionally different parts: a C-terminal catalytic domain, a central dimerization domain, and an N-terminal regulatory domain. The central...

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PMID: 16082162
DOI: 10.2108/zsj.22.735

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CBS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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