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Article

Genetic evidence for a distinct subtype of schizophrenia characterized by pervasive cognitive deficit.

American journal of human genetics - 1 Sept 2005

Hallmayer Joachim F, Kalaydjieva Luba, Badcock Johanna, Dragovic Milan, Howell Sarah, Michie Patricia T, Rock Daniel, Vile David, Williams Rachael, Corder Elizabeth H, Hollingsworth Kate, Jablensky Assen

Abstract excerpt

A novel phenotyping strategy in schizophrenia, targeting different neurocognitive domains, neurobehavioral features, and selected personality traits, has allowed us to identify a homogeneous familial subtype of the disease, characterized by pervasive neurocognitive deficit. Our genome scan data indicate that this subtype, which accounts for up to 50% of our sample, has a distinct genetic basis and explains...

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Identifiers

PMID: 16080121
DOI: 10.1086/432816
PMCID: PMC1226211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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