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Article

Physiological ageing: role of p53 and PARP-1 tumor suppressors in the regulation of terminal senescence.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society - 1 Mar 2005

Wesierska-Gadek J, Ranftler C, Schmid G

Abstract excerpt

Ageing of organisms is among the most complex processes currently known. Understanding the molecular mechanism of physiological ageing is one of the most essential issues in biology and medicine because it is not possible to predict when and how a certain individual will start ageing. In the past centuries human life expectancies increased. Extension of life span is associated with increased susceptibility to a...

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Source

Identifiers

PMID: 16077192

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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