Article
Microarray analysis identifies apoptosis regulatory gene expression in HCT116 cells infected with thermostable direct hemolysin-deletion mutant of Vibrio parahaemolyticus.
Biochemical and biophysical research communications - 23 Sept 2005
Bhattacharjee Rabindra N, Park Kwon-Sam, Okada Kazuhisa, Kumagai Yutaro, Uematsu Satoshi, Takeuchi Osamu, Akira Shizuo, Iida Tetsuya, Honda Takeshi
Abstract excerpt
The thermostable direct hemolysin (TDH) is considered as a major virulence factor of Vibrio parahaemolyticus. We observed this potential in several human cancer cell lines by using the TDH-producing wild-type (RIMD2210633) as well as tdh-deletion mutant of V. parahaemolyticus and found that the deletion of tdh did not affect cytotoxicity to any of the cell lines tested. DNA fragmentation and annexin V staining...
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