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Article

Chromosome 1p loss: A favorable prognostic factor in low‐grade gliomas

27 Jul 2005

Abstract excerpt

Search for loss of heterozygosity on chromosomes 1p, 9p, 10q, and 19q, epidermal growth factor receptor (EGFR) gene amplification, and p53 expression was performed in a series of 131 low-grade gliomas. The profile of molecular changes, clinical findings, and histology were subsequently correlated with the course of the disease, mainly progression-free survival. When these parameters were considered as candidate...

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PMID: 16049942
DOI: 10.1002/ana.20543

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