Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.

doi:10.1007/s10552-005-1724-1

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Article

Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.

Cancer causes & control : CCC - 1 Aug 2005

Kotsopoulos Joanne, Lubinski Jan, Lynch Henry T, Neuhausen Susan L, Ghadirian Parviz, Isaacs Claudine, Weber Barbara, Kim-Sing Charmaine, Foulkes William D, Gershoni-Baruch Ruth, Ainsworth Peter, Friedman Eitan, Daly Mary, Garber Judy E, Karlan Beth, Olopade Olufunmilayo I, Tung Nadine, Saal Howard M, Eisen Andrea, Osborne Michael, Olsson Hakan, Gilchrist Dawna, Sun Ping, Narod Steven A

Abstract excerpt

Age at menarche is a strong and consistent predictor of breast cancer risk in the general population, but has not been well studied in women with a family history of breast cancer. We conducted this study to examine whether the presence of a deleterious BRCA1 or BRCA2 mutation influences age at menarche and to investigate whether or not there is an association between age at menarche and the risk of breast cancer...

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Identifiers

PMID: 16049805
DOI: 10.1007/s10552-005-1724-1

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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